■講演概要
Date: October 17, 2000 8:45〜17:30
 Farewell Party 18:30〜
Place: Communication Center of Hirosaki University School of Medicine, Hirosaki, Japan
Tel: 0172-33-4056
Registration Fee & Farewell Party: ¥2,000
Registration: October 17, 2000 8:15〜
日時:2000年10月17日[火] 8:45〜17:30
   懇親会18:30〜
場所:弘前大学医学部コミュニケーションセンター
参加費:¥2,000(含む懇親会費)
    事前の申込は不要です。 当日8:15より受付を致します。

Invited lecturers
 Yu-Teh Li (Tulane University School of Medicine)
 Veer P. Bhavanandan (The Pennsylvania State University)
 Richard L. Proia (National Institutes of Health)
 Mark D. Brown (University of Miami School of Medicine)
 

Secretariat/Department of Biochemistry
Hirosaki University School of Medicine
 5 Zaifu-cho, Hirosaki 036-8562, Japan
事務局/弘前大学医学部生化学第一講座
 〒036‐8562 青森県弘前市在府町5番地
 Tel: 0172‐39‐5015 Fax: 0172‐39‐5016
 E-mail: endo-m@cc.hirosaki-u.ac.jp
 
 ■PROGRAM
   [ORAL SESSIONS]
8:15 REGISTRATION
8:45-9:00
(15)
OPENING
OPENING REMARKS
Endo M
President, Hirosaki International Forum of Medical Science, Secretary General, Organizing Committee, The 4th Meeting of Hirosaki International Forum of Medical Science Dean, Hirosaki University School of Medicine
WELCOME SPEECH
Nakamura S
Vice-President, Hirosaki University
[SESSION I] METABOLISM OF GLYCOLIPIDS AND PATHOLOGY
Chairpersons: Li SC
(Department of Biochemistry, Tulane University School of Medicine, New Orleans, LA, USA),
Tsuchida S
(Department of Biochemistry, Hirosaki University School of Medicine, Hirosaki, Japan)
9:00-9:40
(40)
I-1 CATABOLISM OF GM2 IN MAN AND MOUSE
Li YT, and Li SC
Department of Biochemistry, Tulane University School of Medici ne, New Orleans, LA, USA
9:40-10:20
(40)
I-2 GLYCOSPHINGOLIPID BIOLOGY AND DESEASE

Proia RL
Genetics of Development and Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institut es of Health, Bethesda, MD, USA

10:20-10:35
(15)
I-3 MICROGLIAL ACTIVATION AND INFLAMMATORY REACTION PRECEDING NEURODEGENERATION IN SANDHOFF DISEASE
Wada R1, 2, Tifft CJ2, 3, and Proia RL2
1Department of Pathology, Hirosaki University School of Medicine, H irosaki, Japan 2Genetics of Development and Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institu tes of Health, Bethesda, MD, USA, 3Department of Medical Gen etics, Children's National Medical Center, Washington, DC, USA
10:35-11:00
(25)
I-4 TISSUE SPECIFIC CONTROL OF GLYCO-CHAINS

Suzuki A1, Omae F1, Enomoto A1, Yoshioka S1, Sekine M2, Kikkawa Y2, Taya C2, Yonekawa H2, Takenaka M3, Matsuoka Y3, Imai E 3, Izawa M4, and Kannagi R4
1Sphingolipid Expression Laboratory, RIKEN Frontier Research System, Tokorozawa, 2Department of Laboratory Animal Science, Tokyo Metropolitan Institute of Medical Science, Tokyo, 3The First Department of Medicine, Osaka University School of Medicine, Osaka, and 4Program of Experimental Pathology, Aichi Cancer Center, Aichi, Japan

11:00-11:20 (20) COFFEE BREAK AND DISCUSSION OF POSTERS
[SESSION II] ROLES OF N-GLYCANS IN TISSUES
Chairpersons: Suzuki A
(Sphingolipid Expression Laboratory, RIKEN Frontier Research System, Tokorozawa, Japan),
Sasaki M
(Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan)
11:20-11:45
(25)
II-1 MALIGNANT TRANSFORMATION-ASSOCIATED CHANGES IN GENE EXPRESSION OF -1,4-GALACTOSYLTRANSFERASES

Furukawa K1, Sato T1, Guo S1, 2, and Shirane K1, 3
1Department of Biosignal Research, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan, 2Department of Pathology, Beijing Medical University, China, and 3 Nissin Flour Milling Co. Ltd., Tokyo, Japan

11:45-12:00
(15)
II-2 CHEMICAL STRUCTURE OF THE CARBOHYDRATE MOIETY OF FUCOSE-RICH GLYCOPEPTIDES FROM HUMAN PANCREATIC JUICE
Yoshihara S, Ichinohe K, Shibata S, Toyoki Y, and Sasaki M
Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
12:00-13:00 (60) LUNCH
[SESSION III] MUCIN AS A BIOGENIC MESSENGER
  Chairpersons: Inazu T
(The Noguchi Institute, Tokyo, Japan),
Munakata A
(First Department of Internal Medicine, Hirosaki University School of Medicine, Hirosaki, Japan)
13:00-13:25
(25)
III-1 MUC1 AS A HUMAN TUMOR MARKER

Imai K, Hayashi T, Suwa T, Makiguchi Y, Itoh F, Hinoda Y, and Takahashi T
First Department of Internal Medicine, Sapporo Medical Universit y School of Medicine, Sapporo, Japan

13:25-13:40
(15)
III-2 CHARACTERIZATION OF MUCIN IN WHOLE-GUT LAVAGE FLUID OBTAINED FROM PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Saitoh H, Tanaka H, Muramoto K, Kimura S, Kubo K, Kas ai M, Yoshida Y, and Munakata A
First Department of Internal Medicine, Hirosaki University Schoo l of Medicine, Hirosaki, Japan

13:40-13:50 (10) COFFEE BREAK
[SESSION IV] ROLES OF PROTEOGLYCANS IN TISSUE ORGANIZATION
  Chairpersons: Ishihara M
(Division of Biomedical Engineering, Research Institute, National Defense Medical College, Tokorozaw a, Japan).
Harata S
(Department of Orthopedics, Hirosaki University School of Medicine, Hirosaki, Japan)
13:50-14:30
(40)
IV-1 THE RATIONALE FOR AND RESULTS OF PRE-CLI NICAL TRIALS OF CHONDROITINASE ABC IN CHEMONUCLEOLYSIS
Brown MD
Department of Orthopedics and Rehabilitation, University of Miami School of Medicine, Miami, FL, USA
   
14:30-14:45
(15)
IV-2 CHANGES IN GLYCOSAMINOGLYCAN CHAINS OF NUCLEUS PULPOSUS PROTEOGLYCAN OF BABOON VERTEBRAL DISCS WITH AGING
Nakamura W, Yukawa M, Takeuchi K, and Harata S
Department of Orthopedics, Hirosaki University School of Medicine, H irosaki, Japan
14:45-15:10
(25)
IV-3 THE ROLE OF HYALURONAN IN THE TUMOR FORMATION OF H-ras-TRANSFORMED RAT FIBROBLASTS
Sawai T 1, 2, Itano N 1, Hamaguchi M 3, Miyaishi O 4, and Kimata K 1
1Institute for Molecular Science of Medicine, Aichi Medical Univ ersity, 2Department of Orthopedics Surgery, Jikei University School of Medicine, 3Department of Molecular Pathogenesis, Nagoya University School of Medicine, and 4Department of Basic Gerontology, National Institute for Longevity Sciences, Japan
15:10-16:00 (50) COFFEE BREAK AND DISCUSSION OF POSTERS
[SESSION V] NEW DEVELOPMENTS OF GLYCOSAMINOGLYCANS FOR CLINICAL APPLICATIONS
Chairpersons: Kimata K ,
(Institute for Molecular Science of Medicine, Aichi Medical University, Aichi, Japan)
Saito Y
(Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Japan)
16:00-16:40
(40)
V-1 USE OF GLYCOSAMINOGLYCANS FOR THE TREATMENT OF INTERSTITIAL CYSTITIS - A STRATEGY TO IMPROVE EFFICACY
Bhavanandan VP1, Erickson DR2, Herb N1, Sheykhnazari M1, and Ordille S2
1Department of Biochemistry and Molecular Biology, 2Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, PA, USA
16:40-16:55
(15)
V-2 ENZYMATIC RECONSTRUCTION OF GLYCOSAMINOGLYCAN OLIGOSACCHARIDES
Takagaki K, Kakizaki I, Iwafune M, Ishido K and Endo M
Department of Biochemistry, Hirosaki University School of Medicine, Hirosaki, Japan
16:55-17:10
(15)
V-3 4-METHYLUMBELLIFERONE INHIBITS HYALUYRONATE SHYNTHESIS INCULTURED FIBROBLASTS FROM THE HUMAN UTERINE CERVIX
Tanaka K, Higuchi T, Sato S, and Saito Y
Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Japan
17:10-17:20
(10)
CLOSING
CLOSING REMARKS

Harata S
Director, Hirosaki University Hospital, A Member of the Organizing Committee, The 4th Meeting of Hirosaki International Forum of Medical Science

17:20-17:30
(10)
BUSINESS MEETING
Hirosaki International Forum of Medical Science 2000
 
 ■Farewell Party
All participants are invited to the concert and the farewell banquet!
Hotel New Castle 4th Floor (Reiho-no-ma), Tuesday, October 17
18:30-19:00 Concert
Jubilee Chamber Ensemble of the Hirosaki University School of Medicine
19:00-21:00 Farewell Banquet