
Table 1	Distribution of major gangliosides in rat nervous system detected by MAbs

Rat region		Ganglioside

Rat region		GM1	GD1a	GD1b	GT1b	GQ1b

Cerebellar cortex
	Molecular layer	+	+++	+	++	-

	Purkinje cell layer	-	-	-	-	-

	Granular layer	+	+	+++	+++	++

	White matter	+++	-	-	+	-

Cerebral cortex
	Molecular layer (I)	+	+++	-	+	-

	Ext. granular layer (II)	+	+++	+	-	-

	Ext. pyramidal layer (III)	+	+++	++	++	-

	Int. granular layer (IV)	+	-	+++	+	+

	Int. pyramidal layer (Va)	+	+	+++	++	-

	Int. pyramidal layer (Vb)	+	-	+++	++	+

	Polymorphic cell layer (VI)	+	+	+++	+	+

	White matter	++	-	+	+++	-

Hippocampal formation
Hippocampus
	Alveus	++	-	++	++	+++

	Stratum oriens	++	++	-	+	+

	Stratum pyramidale	-	-	+	-	++

	Stratum radiatum	-	++	-	+	-

	Stratum lacunosummolelulare	++	-	++	+	-

Dentate gyrus
	Polymorphic layer	+	++	+	+	-

	Granular layer	-	-	++	-	-

	Molecular layer	+	++	-	++	-

Spinal cord
Gray matter
	Anterior horn	+	-	+++	+++	++

	Posterior horn	+	+++	+++	+++	++

White matter
	Anterior funiculus	+	-	+	++	-

	Lateral funiculus	+	-	+	++	-

	Posterior funiculus	+	-	+	++	-

¹Gangliosides GM1, GD1a, GD1b, GT1b,and GQ1b were detected by five MAbs GMB16, GMR17, GGR12, GMR5, and GMR13, respectively, with indirect immunofluorescence technique. ²+++, strong; ++, moderate; +, weak; -, negative.

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