Endo-β-N-acetylglucosaminidase (ENGase) is an enzyme widely distributed among various organisms and known to hydrolyze N-glycans. Recent studies have demonstrated that strategic modification of its catalytic residues enables its conversion into a glycosynthase, thereby facilitating the chemoenzymatic remodeling of N-glycan structures.
In this series, we will discuss recent progress in glycoengineering-related ENGase research by leading experts in each field....and more
